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Cytoprotective mechanism of the novel gastric peptide BPC157 in Gastrointestinal tract and cultured enteric neurons and glial cells

For example, one study revealed that an overexpression of GPX1 inhibited the nucleus-translocation of apoptosis-inducing factor (AIF) from mitochondria in neuronal cells after ischemia-induced apoptosis ( Finally, we explored the possible signaling pathways by which GPX1 was involved in protecting SGNs against peroxynitrite-induced injury

Proteins involved in ROS detoxification, such as SodA and TpxD, contribute to this persistence mechanism [8]

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